Habitual sleep duration and insomnia and the risk of cardiovascular events and all-cause death: report from a community-based cohort.
Sleep
; 33(2): 177-84, 2010 Feb.
Article
in En
| MEDLINE
| ID: mdl-20175401
ABSTRACT
STUDY OBJECTIVES:
To investigate the relationship between sleep duration and insomnia severity and the risk of all-cause death and cardiovascular disease (CVD) events.DESIGN:
Prospective cohort study.SETTING:
Community-based.PARTICIPANTS:
A total of 3,430 adults aged 35 years or older. INTERVENTION None. MEASUREMENTS ANDRESULTS:
During a median 15.9 year (interquartile range, 13.1 to 16.9) follow-up period, 420 cases developed cardiovascular disease and 901 cases died. A U-shape association between sleep duration and all-cause death was found the age and gender-adjusted relative risks (95% confidence interval [CI]) of all-cause death (with 7 h of daily sleep being considered for the reference group) for individuals reporting < or = 5 h, 6 h, 8 h, and > or = 9 h were 1.15 (0.91-1.45), 1.02 (0.85-1.25), 1.05 (0.88-1.27), and 1.43 (1.16-1.75); P for trend, 0.019. However, the relationship between sleep duration and risk of CVD were linear. The multivariate-adjusted relative risk (95% CI) for all-cause death (using individuals without insomnia) were 1.02 (0.86-1.20) for occasional insomnia, 1.15 (0.92-1.42) for frequent insomnia, and 1.70 (1.16-2.49) for nearly everyday insomnia (P for trend, 0.028). The multivariate adjusted relative risk (95% CI) was 2.53 (1.71-3.76) for all-cause death and 2.07 (1.11-3.85) for CVD rate in participants sleeping > or = 9 h and for those with frequent insomnia.CONCLUSIONS:
Sleep duration and insomnia severity were associated with all-cause death and CVD events among ethnic Chinese in Taiwan. Our data indicate that an optimal sleep duration (7-8 h) predicted fewer deaths.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sleep
/
Cardiovascular Diseases
/
Cause of Death
/
Habits
/
Sleep Initiation and Maintenance Disorders
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Asia
Language:
En
Journal:
Sleep
Year:
2010
Type:
Article
Affiliation country:
Taiwan