Microbe-dendritic cell dialog controls regulatory T-cell fate.
Immunol Rev
; 234(1): 305-16, 2010 Mar.
Article
in En
| MEDLINE
| ID: mdl-20193027
ABSTRACT
Each microenvironment is controlled by a specific set of regulatory elements that have to be finely and constantly tuned to maintain local homeostasis. These environments could be site specific, such as the gut environment, or induced by chronic exposure to microbes. Various populations of dendritic cells are central to the orchestration of this control. In this review, we discuss some new findings associating dendritic cells from defined compartments with the induction and control of regulatory T cells in the context of exposure to both commensal and pathogenic microbes.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Parasites
/
Bacteria
/
Dendritic Cells
/
Cell Differentiation
/
T-Lymphocytes, Regulatory
/
Cell Lineage
/
Intestines
Limits:
Animals
/
Humans
Language:
En
Journal:
Immunol Rev
Year:
2010
Type:
Article
Affiliation country:
United States