Particle size and activation threshold: a new dimension of danger signaling.

Rettig, Lorna; Haen, Sebastian P; Bittermann, Anne Greet; von Boehmer, Lotta; Curioni, Alessandra; Krämer, Stefanie D; Knuth, Alexander; Pascolo, Steve

Rettig, Lorna; Haen, Sebastian P; Bittermann, Anne Greet; von Boehmer, Lotta; Curioni, Alessandra; Krämer, Stefanie D; Knuth, Alexander; Pascolo, Steve.

Affiliation

Rettig L; Department of Oncology, University Hospital of Zürich, Zürich, Switzerland.

Blood ; 115(22): 4533-41, 2010 Jun 03.

Article in En | MEDLINE | ID: mdl-20304804

Subject(s)

RNA/chemistry; RNA/immunology; Signal Transduction/immunology; Adjuvants, Immunologic/chemistry; Adjuvants, Immunologic/genetics; Adjuvants, Immunologic/pharmacology; Animals; Base Sequence; Dendritic Cells/immunology; Humans; Immunity, Innate; In Vitro Techniques; Interferon-alpha/biosynthesis; Membrane Glycoproteins/deficiency; Membrane Glycoproteins/genetics; Membrane Glycoproteins/immunology; Mice; Mice, Inbred C57BL; Mice, Knockout; Nanoparticles/chemistry; Oligodeoxyribonucleotides/chemistry; Oligodeoxyribonucleotides/genetics; Oligodeoxyribonucleotides/immunology; Oligodeoxyribonucleotides/pharmacology; Particle Size; Phagocytosis; Protamines/chemistry; Protamines/immunology; RNA/genetics; RNA/pharmacology; RNA Stability; Signal Transduction/genetics; Toll-Like Receptor 7/deficiency; Toll-Like Receptor 7/genetics; Toll-Like Receptor 7/immunology; Tumor Necrosis Factor-alpha/biosynthesis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA / Signal Transduction Language: En Journal: Blood Year: 2010 Type: Article Affiliation country: Switzerland

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