Cell cycle-specific expression and nuclear binding of DNA polymerase alpha.
Mol Cell Biol
; 11(6): 3384-9, 1991 Jun.
Article
in En
| MEDLINE
| ID: mdl-2038340
ABSTRACT
The expression and distribution of DNA polymerase alpha was measured by cytometry and confocal laser scanning microscopy. Expression was proportional to DNA content in proliferating cells, while only S-phase cells retained DNA polymerase alpha after detergent extraction. Nuclear DNA polymerase alpha binding may be one of the key events of S-phase entry.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cell Cycle
/
Cell Nucleus
/
DNA Polymerase II
Limits:
Animals
/
Humans
Language:
En
Journal:
Mol Cell Biol
Year:
1991
Type:
Article