Metastatic pancreatic endocrine tumor presenting as thoracic spinal cord compression.
Spine (Phila Pa 1976)
; 35(11): E510-3, 2010 May 15.
Article
in En
| MEDLINE
| ID: mdl-20421860
ABSTRACT
STUDY DESIGN:
A case report.OBJECTIVE:
The authors present a rare case of metastatic nonfunctioning neuroendocrine tumor of the pancreas presenting as thoracic spinal cord compression. SUMMARY OF BACKGROUND DATA Pancreatic endocrine tumors (PETs) are a slow-growing subset of pancreatic tumors. They can be classified as either functioning or nonfunctioning. To our knowledge, this is the second reported case of a PET presenting as spinal cord compression.METHODS:
The clinical course, radiologic features, pathology, and outcome of the metastasis of PET are reported.RESULTS:
A 59-year-old woman presenting with a 2-week history of midthoracic back pain and early signs of myelopathy. A computed tomography scan and magnetic resonance imaging revealed multiple mildly enhancing lesions within T5, T7, T8, and L1 vertebral bodies with ventral epidural and bilateral T8-T9 neuroforaminal soft tissue extension causing severe spinal canal stenosis. A computed tomography-guided biopsy was inconclusive, and we performed a T7-T9 laminectomy with T8 bilateral transpedicular decompression and T6 to T10 pedicle screw fixation and posterolateral fusion with subtotal resection of the tumor. Pathology was consistent with low-grade neuroendocrine tumor. The patient recovered well, and an octreotide scan ultimately revealed an area of abnormal uptake within the body of the pancreas.CONCLUSION:
We have reported a rare case of a metastatic PET presenting as spinal cord compression.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pancreatic Neoplasms
/
Spinal Cord Compression
/
Spinal Neoplasms
/
Thoracic Vertebrae
/
Carcinoma, Neuroendocrine
Type of study:
Diagnostic_studies
Limits:
Female
/
Humans
/
Middle aged
Language:
En
Journal:
Spine (Phila Pa 1976)
Year:
2010
Type:
Article
Affiliation country:
United States