Optimisation of a pyrazole series of progesterone antagonists; Part 1.
Bioorg Med Chem Lett
; 20(11): 3384-6, 2010 Jun 01.
Article
in En
| MEDLINE
| ID: mdl-20430618
ABSTRACT
The design and synthesis of a novel series of non-steroidal progesterone receptor antagonists is described. Ligand-lipophilicity efficiency (LLE) was used in the selection of a prototype agent for in vivo pharmacology studies.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Progesterone
/
Pyrazoles
Language:
En
Journal:
Bioorg Med Chem Lett
Journal subject:
BIOQUIMICA
/
QUIMICA
Year:
2010
Type:
Article
Affiliation country:
United kingdom