Longitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline.

O'Brien, J L; O'Keefe, K M; LaViolette, P S; DeLuca, A N; Blacker, D; Dickerson, B C; Sperling, R A

O'Brien, J L; O'Keefe, K M; LaViolette, P S; DeLuca, A N; Blacker, D; Dickerson, B C; Sperling, R A.

Affiliation

O'Brien JL; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.

Neurology ; 74(24): 1969-76, 2010 Jun 15.

Article in En | MEDLINE | ID: mdl-20463288

Subject(s)

Aging/metabolism; Dementia/metabolism; Hippocampus/metabolism; Magnetic Resonance Imaging/trends; Aged; Aged, 80 and over; Aging/psychology; Cohort Studies; Dementia/diagnosis; Dementia/psychology; Follow-Up Studies; Humans; Longitudinal Studies; Neuropsychological Tests; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Magnetic Resonance Imaging / Dementia / Hippocampus Type of study: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Aged80 / Humans Language: En Journal: Neurology Year: 2010 Type: Article Affiliation country: United States

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