Hydralazine does not ameliorate nitric oxide resistance in chronic heart failure.

Chirkov, Yuliy Y; De Sciscio, Michele; Sverdlov, Aaron L; Leslie, Sue; Sage, Peter R; Horowitz, John D

Chirkov, Yuliy Y; De Sciscio, Michele; Sverdlov, Aaron L; Leslie, Sue; Sage, Peter R; Horowitz, John D.

Affiliation

Chirkov YY; Cardiology Unit, Vascular Disease and Therapeutics Research Group, Basil Hetzel Institute, The Queen Elizabeth Hospital, School of Medicine, The University of Adelaide, Adelaide, Australia.

Cardiovasc Drugs Ther ; 24(2): 131-7, 2010 Apr.

Article in En | MEDLINE | ID: mdl-20490904

Subject(s)

Drug Resistance/drug effects; Heart Failure/drug therapy; Hydralazine/therapeutic use; Nitric Oxide/pharmacology; Adenosine Diphosphate/pharmacology; Aged; Blood/drug effects; Blood/metabolism; Blood Pressure/drug effects; Cross-Over Studies; Double-Blind Method; Female; Heart Failure/metabolism; Heart Failure/physiopathology; Heart Rate/drug effects; Hemodynamics/drug effects; Humans; Hydralazine/pharmacology; Male; Manometry; Middle Aged; Nitric Oxide Donors/pharmacology; Nitroglycerin/pharmacology; Nitroprusside/pharmacology; Platelet Aggregation/drug effects; Pulse; Superoxides/metabolism; Vasodilation/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Resistance / Heart Failure / Hydralazine / Nitric Oxide Type of study: Clinical_trials Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Cardiovasc Drugs Ther Journal subject: ANGIOLOGIA / CARDIOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2010 Type: Article Affiliation country: Australia

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