Reversing interleukin-2 inhibition mediated by anti-double-stranded DNA autoantibody ameliorates glomerulonephritis in MRL-lpr/lpr mice.

Song, Ying-Chyi; Tang, Shye-Jye; Lee, Tai-Ping; Hung, Wen-Chien; Lin, Shu-Chi; Tsai, Chang-Youh; Ng, Wailap Victor; Wu, Ming-Fang; Sun, Kuang-Hui

Song, Ying-Chyi; Tang, Shye-Jye; Lee, Tai-Ping; Hung, Wen-Chien; Lin, Shu-Chi; Tsai, Chang-Youh; Ng, Wailap Victor; Wu, Ming-Fang; Sun, Kuang-Hui.

Affiliation

Song YC; National Yang-Ming University, Taipei, Taiwan.

Arthritis Rheum ; 62(8): 2401-11, 2010 Aug.

Article in En | MEDLINE | ID: mdl-20506162

Subject(s)

Autoantibodies/immunology; DNA/immunology; Glomerulonephritis/immunology; Interleukin-2/immunology; Lupus Erythematosus, Systemic/immunology; T-Lymphocytes/immunology; Animals; Antibodies, Monoclonal/genetics; Antibodies, Monoclonal/immunology; Autoantibodies/genetics; Blotting, Western; Cell Line; Cells, Cultured; DNA/genetics; Enzyme-Linked Immunosorbent Assay; Female; Glomerulonephritis/genetics; Humans; Interleukin-2/genetics; Lupus Erythematosus, Systemic/genetics; Mice; Mice, Inbred MRL lpr; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction/genetics; Signal Transduction/immunology; T-Lymphocytes/cytology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoantibodies / DNA / T-Lymphocytes / Interleukin-2 / Glomerulonephritis / Lupus Erythematosus, Systemic Limits: Animals / Female / Humans Language: En Journal: Arthritis Rheum Year: 2010 Type: Article Affiliation country: Taiwan

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