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Outcomes of endovascular repair of ruptured descending thoracic aortic aneurysms.
Jonker, Frederik H W; Verhagen, Hence J M; Lin, Peter H; Heijmen, Robin H; Trimarchi, Santi; Lee, W Anthony; Moll, Frans L; Athamneh, Husam; Muhs, Bart E.
Affiliation
  • Jonker FH; Yale University School of Medicine, New Haven, CT 06510, USA.
Circulation ; 121(25): 2718-23, 2010 Jun 29.
Article in En | MEDLINE | ID: mdl-20547930
ABSTRACT

BACKGROUND:

Thoracic endovascular aortic repair offers a less invasive approach for the treatment of ruptured descending thoracic aortic aneurysms (rDTAA). Due to the low incidence of this life-threatening condition, little is known about the outcomes of endovascular repair of rDTAA and the factors that affect these outcomes. METHODS AND

RESULTS:

We retrospectively investigated the outcomes of 87 patients who underwent thoracic endovascular aortic repair for rDTAA at 7 referral centers between 2002 and 2009. The mean age was 69.8+/-12 years and 69.0% of the patients were men. Hypovolemic shock was present in 21.8% of patients, and 40.2% were hemodynamically unstable. The 30-day mortality rate was 18.4%, and hypovolemic shock (odds ratio 4.75; 95% confidence interval, 1.37 to 16.5; P=0.014) and hemothorax at admission (odds ratio 6.65; 95% confidence interval, 1.64 to 27.1; P=0.008) were associated with increased 30-day mortality after adjusting for age. Stroke and paraplegia occurred each in 8.0%, and endoleak was diagnosed in 18.4% of patients within the first 30 days after thoracic endovascular aortic repair. Four additional patients died as a result of procedure-related complications during a median follow-up of 13 months; the estimated aneurysm-related mortality at 4 years was 25.4%.

CONCLUSIONS:

Endovascular repair of rDTAA is associated with encouraging results. The endovascular approach was associated with considerable rates of neurological complications and procedure-related complications such as endoleak.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aortic Rupture / Aortic Aneurysm, Thoracic Type of study: Observational_studies / Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Circulation Year: 2010 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aortic Rupture / Aortic Aneurysm, Thoracic Type of study: Observational_studies / Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Circulation Year: 2010 Type: Article Affiliation country: United States