Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia.

Adamo, Adele; Collis, Spencer J; Adelman, Carrie A; Silva, Nicola; Horejsi, Zuzana; Ward, Jordan D; Martinez-Perez, Enrique; Boulton, Simon J; La Volpe, Adriana

Adamo, Adele; Collis, Spencer J; Adelman, Carrie A; Silva, Nicola; Horejsi, Zuzana; Ward, Jordan D; Martinez-Perez, Enrique; Boulton, Simon J; La Volpe, Adriana.

Affiliation

Adamo A; Institute of Genetics and Biophysics Adriano Buzzati-Traverso, CNR, Via Pietro Castellino 111, 80131, Napoli, Italy.

Mol Cell ; 39(1): 25-35, 2010 Jul 09.

Article in En | MEDLINE | ID: mdl-20598602

Subject(s)

DNA Repair/genetics; Fanconi Anemia/genetics; Recombination, Genetic; Animals; Caenorhabditis elegans/enzymology; Caenorhabditis elegans/genetics; Caenorhabditis elegans Proteins/metabolism; Cross-Linking Reagents/metabolism; Crossing Over, Genetic; DNA Breaks, Double-Stranded; DNA Replication; DNA-Activated Protein Kinase/metabolism; Fanconi Anemia/pathology; Fanconi Anemia Complementation Group D2 Protein/deficiency; Fanconi Anemia Complementation Group D2 Protein/metabolism; Humans; Meiosis/genetics; Mutation/genetics; Rad51 Recombinase/metabolism; Stress, Physiological

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombination, Genetic / DNA Repair / Fanconi Anemia Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2010 Type: Article Affiliation country: Italy

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