PLP/DM20 expression and turnover in a transgenic mouse model of Pelizaeus-Merzbacher disease.

Karim, Saadia A; Barrie, Jennifer A; McCulloch, Mailis C; Montague, Paul; Edgar, Julia M; Iden, Debrah L; Anderson, Thomas J; Nave, Klaus-Armin; Griffiths, Ian R; McLaughlin, Mark

Karim, Saadia A; Barrie, Jennifer A; McCulloch, Mailis C; Montague, Paul; Edgar, Julia M; Iden, Debrah L; Anderson, Thomas J; Nave, Klaus-Armin; Griffiths, Ian R; McLaughlin, Mark.

Affiliation

Karim SA; The Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Bearsden, Glasgow, G61 1BD, Scotland.

Glia ; 58(14): 1727-38, 2010 Nov 01.

Article in En | MEDLINE | ID: mdl-20629189

Subject(s)

Genetic Predisposition to Disease/genetics; Myelin Proteolipid Protein/genetics; Myelin Sheath/genetics; Myelin Sheath/metabolism; Pelizaeus-Merzbacher Disease/genetics; Pelizaeus-Merzbacher Disease/metabolism; Animals; Cells, Cultured; Disease Models, Animal; Down-Regulation/genetics; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myelin Proteolipid Protein/antagonists & inhibitors; Myelin Proteolipid Protein/biosynthesis; Organ Culture Techniques; RNA Interference/physiology; Vacuoles/metabolism; Vacuoles/ultrastructure

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myelin Proteolipid Protein / Genetic Predisposition to Disease / Pelizaeus-Merzbacher Disease / Myelin Sheath Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Glia Journal subject: NEUROLOGIA Year: 2010 Type: Article Affiliation country: United kingdom

Fulltext

XML

PubMed Links

Search on Google