A standardized framework for the validation and verification of clinical molecular genetic tests.

Mattocks, Christopher J; Morris, Michael A; Matthijs, Gert; Swinnen, Elfriede; Corveleyn, Anniek; Dequeker, Els; Müller, Clemens R; Pratt, Victoria; Wallace, Andrew

Mattocks, Christopher J; Morris, Michael A; Matthijs, Gert; Swinnen, Elfriede; Corveleyn, Anniek; Dequeker, Els; Müller, Clemens R; Pratt, Victoria; Wallace, Andrew.

Affiliation

Mattocks CJ; National Genetics Reference Laboratory (Wessex), Salisbury District Hospital, Salisbury, UK. chris.mattocks@salisbury.nhs.uk

Eur J Hum Genet ; 18(12): 1276-88, 2010 Dec.

Article in En | MEDLINE | ID: mdl-20664632

Subject(s)

Genetic Testing/methods; Genetic Testing/standards; Molecular Biology/methods; Molecular Biology/standards; Validation Studies as Topic; Confidence Intervals; Gene Dosage; Health Plan Implementation; Humans; Polymerase Chain Reaction; Reference Standards; Reproducibility of Results; Sample Size; Sensitivity and Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Testing / Validation Studies as Topic / Molecular Biology Type of study: Diagnostic_studies / Guideline / Prognostic_studies / Sysrev_observational_studies Limits: Humans Language: En Journal: Eur J Hum Genet Journal subject: GENETICA MEDICA Year: 2010 Type: Article Affiliation country: United kingdom

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