Development and evaluation of a novel method for preclinical measurement of tissue vascular volume.

Boswell, C Andrew; Ferl, Gregory Z; Mundo, Eduardo E; Schweiger, Michelle G; Marik, Jan; Reich, Michael P; Theil, Frank-Peter; Fielder, Paul J; Khawli, Leslie A

Boswell, C Andrew; Ferl, Gregory Z; Mundo, Eduardo E; Schweiger, Michelle G; Marik, Jan; Reich, Michael P; Theil, Frank-Peter; Fielder, Paul J; Khawli, Leslie A.

Affiliation

Boswell CA; Department of Pharmacokinetic and Pharmacodynamic Sciences, Genentech Research and Early Development, South San Francisco, CA 94080, USA.

Mol Pharm ; 7(5): 1848-57, 2010 Oct 04.

Article in En | MEDLINE | ID: mdl-20704296

Subject(s)

Blood Volume; Radiopharmaceuticals; Technetium Tc 99m Pyrophosphate; Animals; Antibodies, Monoclonal, Humanized/pharmacokinetics; Blood Vessels/anatomy & histology; Chemistry, Pharmaceutical; Drug Discovery; Erythrocytes/metabolism; Female; Mice; Mice, Nude; Models, Biological; Multimodal Imaging; Pharmacokinetics; Positron-Emission Tomography; Tissue Distribution; Tomography, X-Ray Computed; Trastuzumab

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Volume / Technetium Tc 99m Pyrophosphate / Radiopharmaceuticals Type of study: Evaluation_studies / Guideline / Prognostic_studies Limits: Animals Language: En Journal: Mol Pharm Journal subject: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Year: 2010 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google