Sustained CD28 expression delays multiple features of replicative senescence in human CD8 T lymphocytes.

Parish, Stanley T; Wu, Jennifer E; Effros, Rita B

Parish, Stanley T; Wu, Jennifer E; Effros, Rita B.

Affiliation

Parish ST; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.

J Clin Immunol ; 30(6): 798-805, 2010 Nov.

Article in En | MEDLINE | ID: mdl-20721608

Subject(s)

Aging/immunology; CD28 Antigens/metabolism; CD8-Positive T-Lymphocytes/immunology; Cellular Senescence/immunology; HIV Infections/immunology; Animals; CD28 Antigens/genetics; CD28 Antigens/immunology; Disease Progression; Gene Expression Regulation/immunology; Humans; Signal Transduction/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / HIV Infections / Cellular Senescence / CD28 Antigens / CD8-Positive T-Lymphocytes Limits: Animals / Humans Language: En Journal: J Clin Immunol Year: 2010 Type: Article Affiliation country: United States

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