Forecasting the economic value of an Enterovirus 71 (EV71) vaccine.
Vaccine
; 28(49): 7731-6, 2010 Nov 16.
Article
in En
| MEDLINE
| ID: mdl-20923711
ABSTRACT
Enterovirus 71 (EV71) is a growing public health concern, especially in Asia. A surge of EV71 cases in 2008 prompted authorities in China to go on national alert. While there is currently no treatment for EV71 infections, vaccines are under development. We developed a computer simulation model to determine the potential economic value of an EV71 vaccine for children (<5 years old) in China. Our results suggest that routine vaccination in China (EV71 infection incidence ≈0.04%) may be cost-effective when vaccine cost is $25 and efficacy ≥70% or cost is $10 and efficacy ≥50%. For populations with higher infection risk (≥0.4%), a $50 or $75 vaccine would be highly cost-effective even when vaccine efficacy is as low as 50%.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Viral Vaccines
/
Models, Economic
/
Enterovirus Infections
/
Forecasting
Type of study:
Health_economic_evaluation
/
Prognostic_studies
Limits:
Child
/
Humans
Language:
En
Journal:
Vaccine
Year:
2010
Type:
Article
Affiliation country:
United States