Molecular basis of the mixed lineage leukemia-menin interaction: implications for targeting mixed lineage leukemias.

Grembecka, Jolanta; Belcher, Amalia M; Hartley, Thomas; Cierpicki, Tomasz

Grembecka, Jolanta; Belcher, Amalia M; Hartley, Thomas; Cierpicki, Tomasz.

Affiliation

Grembecka J; Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109, USA. jolantag@umich.edu

J Biol Chem ; 285(52): 40690-8, 2010 Dec 24.

Article in En | MEDLINE | ID: mdl-20961854

Subject(s)

Myeloid-Lymphoid Leukemia Protein/chemistry; Proto-Oncogene Proteins/chemistry; Amino Acid Motifs; Amino Acid Substitution; Histone-Lysine N-Methyltransferase; Humans; Mutagenesis; Myeloid-Lymphoid Leukemia Protein/genetics; Myeloid-Lymphoid Leukemia Protein/metabolism; Nuclear Magnetic Resonance, Biomolecular; Oncogene Proteins, Fusion/chemistry; Oncogene Proteins, Fusion/genetics; Oncogene Proteins, Fusion/metabolism; Protein Structure, Quaternary; Proto-Oncogene Proteins/genetics; Proto-Oncogene Proteins/metabolism; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins / Myeloid-Lymphoid Leukemia Protein Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2010 Type: Article Affiliation country: United States

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