Citron kinase regulates axon growth through a pathway that converges on cofilin downstream of RhoA.

Ahmed, Zubair; Douglas, Michael R; Read, Martin L; Berry, Martin; Logan, Ann

Ahmed, Zubair; Douglas, Michael R; Read, Martin L; Berry, Martin; Logan, Ann.

Affiliation

Ahmed Z; Neuropharmacology and Neurobiology Section, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK. z.ahmed.1@bham.ac.uk

Neurobiol Dis ; 41(2): 421-9, 2011 Feb.

Article in En | MEDLINE | ID: mdl-20971191

Subject(s)

Axons/enzymology; Cofilin 1/metabolism; Growth Cones/enzymology; Intracellular Signaling Peptides and Proteins/physiology; Nerve Regeneration/physiology; Protein Serine-Threonine Kinases/physiology; Signal Transduction/physiology; rhoA GTP-Binding Protein/metabolism; Actins/metabolism; Animals; Axons/physiology; Cells, Cultured; Disease Models, Animal; Down-Regulation/genetics; Down-Regulation/physiology; Intracellular Signaling Peptides and Proteins/genetics; Lim Kinases/physiology; Male; Nerve Regeneration/genetics; Polymerization; Protein Serine-Threonine Kinases/genetics; Rats; Rats, Sprague-Dawley; Signal Transduction/genetics; rho-Associated Kinases/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Axons / Signal Transduction / Protein Serine-Threonine Kinases / Growth Cones / RhoA GTP-Binding Protein / Intracellular Signaling Peptides and Proteins / Cofilin 1 / Nerve Regeneration Type of study: Prognostic_studies Limits: Animals Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2011 Type: Article Affiliation country: United kingdom

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