Corticosterone mediates reciprocal changes in CB 1 and TRPV1 receptors in primary sensory neurons in the chronically stressed rat.

Hong, Shuangsong; Zheng, Gen; Wu, Xiaoyin; Snider, Natasha T; Owyang, Chung; Wiley, John W

Hong, Shuangsong; Zheng, Gen; Wu, Xiaoyin; Snider, Natasha T; Owyang, Chung; Wiley, John W.

Affiliation

Hong S; Department of Internal Medicine, University of Michigan, 1150 W Medical Center Drive, MSRB III, Room 9315, Ann Arbor, Michigan 48109, USA. hongss@med.umich.edu

Gastroenterology ; 140(2): 627-637.e4, 2011 Feb.

Article in En | MEDLINE | ID: mdl-21070780

Subject(s)

Corticosterone/physiology; Hyperalgesia/metabolism; Receptor, Cannabinoid, CB1/metabolism; Sensory Receptor Cells/drug effects; Stress, Psychological/complications; TRPV Cation Channels/metabolism; Animals; Benzoxazines/pharmacology; Chronic Disease; Colon/drug effects; Colon/metabolism; Corticosterone/pharmacology; Disease Models, Animal; Feces; Ganglia, Spinal/drug effects; Hyperalgesia/etiology; Male; Mifepristone/pharmacology; Morpholines/pharmacology; Naphthalenes/pharmacology; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1/analysis; Receptors, Glucocorticoid/antagonists & inhibitors; Sensory Receptor Cells/chemistry; Sensory Receptor Cells/metabolism; Stress, Psychological/metabolism; TRPV Cation Channels/analysis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sensory Receptor Cells / Stress, Psychological / Corticosterone / Receptor, Cannabinoid, CB1 / TRPV Cation Channels / Hyperalgesia Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Gastroenterology Year: 2011 Type: Article Affiliation country: United States

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