The sequence of application of methotrexate and histone deacetylase inhibitors determines either a synergistic or an antagonistic response in childhood acute lymphoblastic leukemia cells. | Leukemia;25(2): 359-61, 2011 Feb. | MEDLINE

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The sequence of application of methotrexate and histone deacetylase inhibitors determines either a synergistic or an antagonistic response in childhood acute lymphoblastic leukemia cells.

Bastian, L; Einsiedel, H G; Henze, G; Seeger, K; Shalapour, S.

Leukemia ; 25(2): 359-61, 2011 Feb.

Article in En | MEDLINE | ID: mdl-21072050

Subject(s)

Histone Deacetylase Inhibitors/administration & dosage; Methotrexate/administration & dosage; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy; Cell Line, Tumor; Child; Drug Antagonism; Drug Synergism; Humans

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Methotrexate / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Histone Deacetylase Inhibitors Limits: Child / Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2011 Type: Article

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Methotrexate / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Histone Deacetylase Inhibitors Limits: Child / Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2011 Type: Article