A new, lineage specific, autoup-regulation mechanism for human glucocorticoid receptor gene expression in 697 pre-B-acute lymphoblastic leukemia cells.

Geng, Chuan-dong; Vedeckis, Wayne V

Geng, Chuan-dong; Vedeckis, Wayne V.

Affiliation

Geng CD; Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA.

Mol Endocrinol ; 25(1): 44-57, 2011 Jan.

Article in En | MEDLINE | ID: mdl-21084380

Subject(s)

Cell Lineage/genetics; Gene Expression Regulation, Leukemic; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/genetics; Receptors, Glucocorticoid/genetics; Up-Regulation/genetics; Apoptosis/drug effects; Base Sequence; Chromatin Immunoprecipitation; Dexamethasone/pharmacology; Gene Expression Regulation, Leukemic/drug effects; Humans; Models, Biological; Molecular Sequence Data; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/pathology; Promoter Regions, Genetic/genetics; Protein Binding/drug effects; Proto-Oncogene Proteins c-myb/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism; Receptors, Glucocorticoid/metabolism; Transcription Factors/metabolism; Up-Regulation/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Receptors, Glucocorticoid / Gene Expression Regulation, Leukemic / Up-Regulation / Cell Lineage Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Endocrinol Journal subject: BIOLOGIA MOLECULAR / ENDOCRINOLOGIA Year: 2011 Type: Article Affiliation country: United States

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