Mechanisms of novel cardioprotective functions of CCN2/CTGF in myocardial ischemia-reperfusion injury.

Ahmed, M Shakil; Gravning, Jørgen; Martinov, Vladimir N; von Lueder, Thomas G; Edvardsen, Thor; Czibik, Gabor; Moe, Ingvild T; Vinge, Leif E; Øie, Erik; Valen, Guro; Attramadal, Håvard

Ahmed, M Shakil; Gravning, Jørgen; Martinov, Vladimir N; von Lueder, Thomas G; Edvardsen, Thor; Czibik, Gabor; Moe, Ingvild T; Vinge, Leif E; Øie, Erik; Valen, Guro; Attramadal, Håvard.

Affiliation

Ahmed MS; Institute for Surgical Research, Department of Cardiology, Center for Heart Failure Research, Oslo University Hospital-Rikshospitalet, University of Oslo, Norway.

Am J Physiol Heart Circ Physiol ; 300(4): H1291-302, 2011 Apr.

Article in En | MEDLINE | ID: mdl-21186275

Subject(s)

Connective Tissue Growth Factor/pharmacology; Myocardial Reperfusion Injury/metabolism; Myocardial Reperfusion Injury/physiopathology; Animals; Cardiotonic Agents/pharmacology; Cells, Cultured; Connective Tissue Growth Factor/genetics; Gene Expression Profiling; Glycogen Synthase Kinase 3/metabolism; Glycogen Synthase Kinase 3 beta; Humans; Male; Mice; Mice, Transgenic; Myocardial Infarction/metabolism; Myocardial Reperfusion Injury/drug therapy; Myocardial Reperfusion Injury/genetics; Myocytes, Cardiac/drug effects; Myocytes, Cardiac/metabolism; Myocytes, Cardiac/physiology; Phosphorylation; Proto-Oncogene Proteins c-akt/metabolism; Ribosomal Protein S6 Kinases, 70-kDa/metabolism; Smad2 Protein/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myocardial Reperfusion Injury / Connective Tissue Growth Factor Limits: Animals / Humans / Male Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2011 Type: Article Affiliation country: Norway

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