Profibrotic phenotype of conjunctival fibroblasts from mucous membrane pemphigoid.

Saw, Valerie P J; Schmidt, Enno; Offiah, Ifeoma; Galatowicz, Grazyna; Zillikens, Detlef; Dart, John K G; Calder, Virginia L; Daniels, Julie T

Saw, Valerie P J; Schmidt, Enno; Offiah, Ifeoma; Galatowicz, Grazyna; Zillikens, Detlef; Dart, John K G; Calder, Virginia L; Daniels, Julie T.

Affiliation

Saw VP; Department of Ocular Biology and Therapeutics, University College London Institute of Ophthalmology, London, UK. v.saw@ucl.ac.uk

Am J Pathol ; 178(1): 187-97, 2011 Jan.

Article in En | MEDLINE | ID: mdl-21224056

Subject(s)

Conjunctiva/pathology; Fibroblasts/pathology; Pemphigoid, Benign Mucous Membrane/pathology; Aged; Aged, 80 and over; Cell Differentiation; Cell Division; Cell Movement; Cells, Cultured; Chemokine CCL11/metabolism; Collagen Type I/metabolism; Conjunctiva/drug effects; Conjunctiva/metabolism; Culture Media, Serum-Free; Female; Fibroblasts/drug effects; Fibroblasts/metabolism; Fibrosis; Humans; Interleukin-13/pharmacology; Male; Matrix Metalloproteinase 13/metabolism; Matrix Metalloproteinase 3/metabolism; Middle Aged; Mucous Membrane/pathology; Myofibroblasts/pathology; Phenotype; Tumor Necrosis Factor-alpha/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pemphigoid, Benign Mucous Membrane / Conjunctiva / Fibroblasts Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Am J Pathol Year: 2011 Type: Article Affiliation country: United kingdom

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