BALB/c mice deficient in CD4 T cell IL-4R&#945; expression control Leishmania mexicana Load although female but not male mice develop a healer phenotype.

Bryson, Karen J; Millington, Owain R; Mokgethi, Thabang; McGachy, H Adrienne; Brombacher, Frank; Alexander, James

BALB/c mice deficient in CD4 T cell IL-4Rα expression control Leishmania mexicana Load although female but not male mice develop a healer phenotype.

Bryson, Karen J; Millington, Owain R; Mokgethi, Thabang; McGachy, H Adrienne; Brombacher, Frank; Alexander, James.

Affiliation

Bryson KJ; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.

PLoS Negl Trop Dis ; 5(1): e930, 2011 Jan 04.

Article in En | MEDLINE | ID: mdl-21245915

Subject(s)

CD4-Positive T-Lymphocytes/immunology; Leishmania mexicana/immunology; Leishmaniasis, Cutaneous/immunology; Leishmaniasis, Cutaneous/mortality; Receptors, Cell Surface/deficiency; Receptors, Cell Surface/immunology; Animals; Female; Interleukin-13/immunology; Interleukin-4/immunology; Leishmania mexicana/pathogenicity; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Sex Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leishmania mexicana / CD4-Positive T-Lymphocytes / Leishmaniasis, Cutaneous / Receptors, Cell Surface Limits: Animals Country/Region as subject: Mexico Language: En Journal: PLoS Negl Trop Dis Journal subject: MEDICINA TROPICAL Year: 2011 Type: Article Affiliation country: United kingdom

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