Evaluation of the toxicity of Adonis aestivalis in sheep.
Vet Rec
; 168(2): 49, 2011 Jan 15.
Article
in En
| MEDLINE
| ID: mdl-21257561
ABSTRACT
To determine the toxicity of Adonis aestivalis (adonis) in sheep, adult Suffolk ewes were administered 1 per cent bodyweight adonis via surgically placed rumen cannulas in an acute, high-dose toxicity study, and 0.2 per cent bodyweight daily in a two-week, low-dose toxicity study. The ewes received cardiac examinations before dosing, 24 and 48 hours after dosing with 1 per cent bodyweight adonis, and after continuous low-dose administration. All the ewes administered adonis had transient sinus arrhythmias after receiving 1 per cent bodyweight adonis. Two of the three ewes had transient reduced fractional shortening after administration with 1 per cent bodyweight adonis; the same two ewes had reduced fractional shortening after the low-dose treatment regimen. No gross or microscopic lesions were seen when the ewes were examined postmortem at the end of the study.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Plant Poisoning
/
Sheep Diseases
/
Toxicity Tests
/
Adonis
Limits:
Animals
Language:
En
Journal:
Vet Rec
Year:
2011
Type:
Article
Affiliation country:
United States