[Surgical treatment of extravasation injuries]. / Chirurgische Behandlung von Paravasaten.
Zentralbl Chir
; 139 Suppl 2: e103-8, 2014 Dec.
Article
in De
| MEDLINE
| ID: mdl-21294083
ABSTRACT
OBJECTIVE:
Extravasations account for most iatrogenic injuries. The aim of the study was to analyse the results of surgery in patients with extravasations and to draw conclusions for future treatment. MATERIALS ANDMETHODS:
24âpatients with soft-tissue defects after extravasations were treated between 1999 and 2009 in our hospital. The cases were analysed retrospectively. We looked at the drugs causing tissue necrosis and the localisation in relation to the number of interventions and reconstruction complexity.RESULTS:
In 83â% (nâ=â20) of cases tissue necrosis was caused by chemotherapeutic agents, in 8â% (nâ=â2) by contrast mediums and in 4â% (nâ=â1) by antibiotics and insulin. 70â% of the cases involved the upper extremity, in 30â% the thoracic wall was affected. 38â% of the extravasations occurred over venous access ports. In mean 2â±â1.5âinterventions were necessary for defect coverage. Two patients died as a direct result of the extravasations, one due to sepsis originating from an infected necrosis area and one due to right-heart failure with prior pulmonary damage.CONCLUSION:
Most extravasations can be treated without surgery. In cases of toxic extravasations or pressure-caused ischaemia rapid surgical intervention is necessary to prevent the necrosis progressing to deeper tissue layers.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Extravasation of Diagnostic and Therapeutic Materials
/
Iatrogenic Disease
Type of study:
Etiology_studies
/
Observational_studies
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
De
Journal:
Zentralbl Chir
Year:
2014
Type:
Article