SIMPLE/LITAF expression induces the translocation of the ubiquitin ligase itch towards the lysosomal compartments.

Eaton, Heather E; Desrochers, Guillaume; Drory, Samuel B; Metcalf, Julie; Angers, Annie; Brunetti, Craig R

Eaton, Heather E; Desrochers, Guillaume; Drory, Samuel B; Metcalf, Julie; Angers, Annie; Brunetti, Craig R.

Affiliation

Eaton HE; Department of Biology, Trent University, Peterborough, Canada.

PLoS One ; 6(2): e16873, 2011 Feb 04.

Article in En | MEDLINE | ID: mdl-21326863

Subject(s)

Lysosomes/metabolism; Nuclear Proteins/genetics; Repressor Proteins/metabolism; Transcription Factors/genetics; Ubiquitin-Protein Ligases/metabolism; Amino Acid Sequence; Animals; Animals, Newborn; Cell Compartmentation; Cell Line; Chlorocebus aethiops; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins/chemistry; Nuclear Proteins/metabolism; Nuclear Proteins/physiology; Protein Binding; Protein Interaction Domains and Motifs/genetics; Protein Interaction Domains and Motifs/physiology; Protein Transport/genetics; Transcription Factors/chemistry; Transcription Factors/metabolism; Transcription Factors/physiology; Up-Regulation/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Transcription Factors / Nuclear Proteins / Ubiquitin-Protein Ligases / Lysosomes Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2011 Type: Article Affiliation country: Canada

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