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Phase I evaluation of telatinib, a VEGF receptor tyrosine kinase inhibitor, in combination with bevacizumab in subjects with advanced solid tumors.
Langenberg, M H G; Witteveen, P O; Roodhart, J; Lolkema, M P; Verheul, H M W; Mergui-Roelvink, M; Brendel, E; Krätzschmar, J; Loembé, B; Nol-Boekel, A; Christensen, O; Schellens, J H M; Voest, E E.
Affiliation
  • Langenberg MHG; Department of Medical Oncology, University Medical Center Utrecht, Utrecht.
  • Witteveen PO; Department of Medical Oncology, University Medical Center Utrecht, Utrecht.
  • Roodhart J; Department of Medical Oncology, University Medical Center Utrecht, Utrecht.
  • Lolkema MP; Department of Medical Oncology, University Medical Center Utrecht, Utrecht.
  • Verheul HMW; Department of Medical Oncology, University Medical Center Utrecht, Utrecht.
  • Mergui-Roelvink M; Department of Medical Oncology, The Netherlands Cancer Institute Amsterdam, Amsterdam, The Netherlands.
  • Brendel E; Department of Pharmacokinetic Analysis, Bayer HealthCare AG, Wuppertal, Germany.
  • Krätzschmar J; Department of Pharmacokinetic Analysis, Bayer HealthCare AG, Wuppertal, Germany.
  • Loembé B; Bayer Schering Pharma, Mijdrecht, The Netherlands.
  • Nol-Boekel A; Department of Medical Oncology, The Netherlands Cancer Institute Amsterdam, Amsterdam, The Netherlands.
  • Christensen O; Bayer Pharmaceuticals Inc., Montville, USA.
  • Schellens JHM; Department of Medical Oncology, The Netherlands Cancer Institute Amsterdam, Amsterdam, The Netherlands; Department of Pharmaceutical Sciences, Division Drug Toxicology, Utrecht University, Utrecht, The Netherlands.
  • Voest EE; Department of Medical Oncology, University Medical Center Utrecht, Utrecht. Electronic address: e.e.voest@umcutrecht.nl.
Ann Oncol ; 22(11): 2508-2515, 2011 Nov.
Article in En | MEDLINE | ID: mdl-21378200
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridazines / Pyridines / Protein-Tyrosine Kinases / Antineoplastic Combined Chemotherapy Protocols / Vascular Endothelial Growth Factor Receptor-1 / Antibodies, Monoclonal, Humanized / Neoplasms Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2011 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridazines / Pyridines / Protein-Tyrosine Kinases / Antineoplastic Combined Chemotherapy Protocols / Vascular Endothelial Growth Factor Receptor-1 / Antibodies, Monoclonal, Humanized / Neoplasms Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2011 Type: Article