RN181 suppresses hepatocellular carcinoma growth by inhibition of the ERK/MAPK pathway.

Wang, Suihai; Huang, Xiang; Li, Yue; Lao, Haimiao; Zhang, Ying; Dong, Huimin; Xu, Weiwen; Li, Ji-Liang; Li, Ming

Wang, Suihai; Huang, Xiang; Li, Yue; Lao, Haimiao; Zhang, Ying; Dong, Huimin; Xu, Weiwen; Li, Ji-Liang; Li, Ming.

Affiliation

Wang S; School of Biotechnology, Southern Medical University, Guangzhou, China.

Hepatology ; 53(6): 1932-42, 2011 Jun.

Article in En | MEDLINE | ID: mdl-21391225

Subject(s)

Carcinoma, Hepatocellular/physiopathology; Cell Proliferation; Liver Neoplasms/physiopathology; Mitogen-Activated Protein Kinase 1/antagonists & inhibitors; Mitogen-Activated Protein Kinase 3/antagonists & inhibitors; Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors; Ubiquitin-Protein Ligases/physiology; Adult; Aged; Animals; Carcinoma, Hepatocellular/pathology; Cell Line, Tumor; Down-Regulation/physiology; Female; Gene Expression Regulation, Neoplastic/physiology; Humans; Liver Neoplasms/pathology; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Signal Transduction/physiology; Xenograft Model Antitumor Assays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Mitogen-Activated Protein Kinase 1 / Mitogen-Activated Protein Kinase Kinases / Ubiquitin-Protein Ligases / Mitogen-Activated Protein Kinase 3 / Cell Proliferation / Liver Neoplasms Limits: Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Hepatology Year: 2011 Type: Article Affiliation country: China

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