p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype.

Freund, Adam; Patil, Christopher K; Campisi, Judith

Freund, Adam; Patil, Christopher K; Campisi, Judith.

Affiliation

Freund A; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.

EMBO J ; 30(8): 1536-48, 2011 Apr 20.

Article in En | MEDLINE | ID: mdl-21399611

Subject(s)

Cellular Senescence; Cytokines/metabolism; DNA Damage; Fibroblasts/metabolism; p38 Mitogen-Activated Protein Kinases/metabolism; Blotting, Western; Cells, Cultured; Chromatin Immunoprecipitation; Fluorescent Antibody Technique; Humans; NF-kappa B/genetics; NF-kappa B/metabolism; Phenotype; Signal Transduction; Tumor Suppressor Protein p53/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Cytokines / Cellular Senescence / P38 Mitogen-Activated Protein Kinases / Fibroblasts Type of study: Risk_factors_studies Limits: Humans Language: En Journal: EMBO J Year: 2011 Type: Article Affiliation country: United States

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