Successful remission of Evans syndrome associated with Graves' disease by using propylthiouracil monotherapy.
Intern Med
; 50(6): 621-5, 2011.
Article
in En
| MEDLINE
| ID: mdl-21422690
ABSTRACT
A 46-year-old woman with Graves' disease was admitted for anemia and thrombocytopenia. She had previously been treated with methimazole but she self-discontinued the treatment 6 months prior to admission. She was diagnosed with Evans syndrome associated with Graves' disease and treated with propylthiouracil without corticosteroids, which normalized her thyroglobulin level. Surprisingly, while Evans syndrome is characterized by frequent relapses, this patient has been in remission of Evans syndrome for approximately 4 years. The remission of Evans syndrome associated with Graves' disease in the absence of immunosuppressive therapy suggests that these 2 diseases have a common pathogenetic mechanism.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Propylthiouracil
/
Thrombocytopenia
/
Graves Disease
/
Anemia, Hemolytic, Autoimmune
Type of study:
Risk_factors_studies
Limits:
Female
/
Humans
Language:
En
Journal:
Intern Med
Journal subject:
MEDICINA INTERNA
Year:
2011
Type:
Article
Affiliation country:
Japan