Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence.

Reese, Michael L; Zeiner, Gusti M; Saeij, Jeroen P J; Boothroyd, John C; Boyle, Jon P

Reese, Michael L; Zeiner, Gusti M; Saeij, Jeroen P J; Boothroyd, John C; Boyle, Jon P.

Affiliation

Reese ML; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Proc Natl Acad Sci U S A ; 108(23): 9625-30, 2011 Jun 07.

Article in En | MEDLINE | ID: mdl-21436047

Subject(s)

Multigene Family/genetics; Polymorphism, Genetic; Protozoan Proteins/genetics; Toxoplasma/genetics; Amino Acid Sequence; Animals; Cells, Cultured; Female; Genetic Complementation Test; Genetic Loci/genetics; Genetic Variation; Humans; Male; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; Phylogeny; Protein Isoforms/genetics; Protozoan Proteins/classification; Sequence Homology, Amino Acid; Species Specificity; Toxoplasma/classification; Toxoplasma/pathogenicity; Toxoplasmosis, Animal/parasitology; Virulence/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Toxoplasma / Protozoan Proteins / Multigene Family Limits: Animals / Female / Humans / Male Language: En Journal: Proc Natl Acad Sci U S A Year: 2011 Type: Article Affiliation country: United States

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