Apposite insulin-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization.

Siddals, Kirk W; Allen, Justine; Sinha, Smeeta; Canfield, Ann E; Kalra, Philip A; Gibson, J Martin

Siddals, Kirk W; Allen, Justine; Sinha, Smeeta; Canfield, Ann E; Kalra, Philip A; Gibson, J Martin.

Affiliation

Siddals KW; Imaging, Genomics, and Proteomics Group, School of Cancer and Enabling Sciences, University of Manchester, Oxford Road, Manchester M13 9PY, United Kingdom. kirk.siddals@manchester.ac.uk

J Biol Chem ; 286(19): 16623-30, 2011 May 13.

Article in En | MEDLINE | ID: mdl-21454560

Subject(s)

Muscle, Smooth, Vascular/metabolism; Receptors, Somatomedin/metabolism; 1-Deoxynojirimycin/pharmacology; Animals; Antiviral Agents/pharmacology; Aorta/metabolism; Cattle; Cell Differentiation; Glycerophosphates/chemistry; Glycosylation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology; MAP Kinase Signaling System; Mevalonic Acid/metabolism; Models, Biological; Osteogenesis; Phenotype; Receptor, IGF Type 1/metabolism; Tunicamycin/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Somatomedin / Muscle, Smooth, Vascular Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2011 Type: Article Affiliation country: United kingdom

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