Identification of a transforming MYB-GATA1 fusion gene in acute basophilic leukemia: a new entity in male infants.

Quelen, Cathy; Lippert, Eric; Struski, Stephanie; Demur, Cécile; Soler, Gwendoline; Prade, Nais; Delabesse, Eric; Broccardo, Cyril; Dastugue, Nicole; Mahon, François-Xavier; Brousset, Pierre

Quelen, Cathy; Lippert, Eric; Struski, Stephanie; Demur, Cécile; Soler, Gwendoline; Prade, Nais; Delabesse, Eric; Broccardo, Cyril; Dastugue, Nicole; Mahon, François-Xavier; Brousset, Pierre.

Affiliation

Quelen C; Inserm, U1037, Centre de Recherche sur le Cancer de Toulouse, Toulouse, France.

Blood ; 117(21): 5719-22, 2011 May 26.

Article in En | MEDLINE | ID: mdl-21474671

Subject(s)

GATA1 Transcription Factor/genetics; Leukemia, Basophilic, Acute/genetics; Oncogene Proteins, Fusion/genetics; Oncogenes/genetics; Proto-Oncogene Proteins c-myb/genetics; Animals; Blotting, Western; Chromosomes, Human, Pair 6/genetics; Chromosomes, Human, X/genetics; Female; Humans; In Situ Hybridization, Fluorescence; Infant; Karyotyping; Male; Mice; Mice, Inbred C57BL; Prognosis; RNA, Messenger/genetics; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic; Tumor Stem Cell Assay

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oncogenes / Leukemia, Basophilic, Acute / Oncogene Proteins, Fusion / Proto-Oncogene Proteins c-myb / GATA1 Transcription Factor Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Female / Humans / Infant / Male Language: En Journal: Blood Year: 2011 Type: Article Affiliation country: France

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