Molecular changes in the esophageal epithelium after a subchronic exposure to cigarette smoke in the presence of bile-acid reflux.

Aiyer, Harini S; Li, Yan; Harper, Nicholas; Myers, Steven R; Martin, Robert C G

Aiyer, Harini S; Li, Yan; Harper, Nicholas; Myers, Steven R; Martin, Robert C G.

Affiliation

Aiyer HS; Division of Surgical Oncology, Department of Surgery, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA.

Inhal Toxicol ; 23(5): 304-11, 2011 Apr.

Article in En | MEDLINE | ID: mdl-21506880

Subject(s)

Bile Reflux/metabolism; Epithelial Cells/drug effects; Esophagitis/metabolism; Esophagus/drug effects; Tobacco Smoke Pollution/adverse effects; Anastomosis, Surgical; Animals; Bile Reflux/etiology; Bile Reflux/pathology; Biomarkers/metabolism; Body Weight/drug effects; Cyclooxygenase 2/metabolism; Disease Models, Animal; Duodenum/surgery; Epithelial Cells/metabolism; Epithelial Cells/pathology; Esophagitis/etiology; Esophagitis/pathology; Esophagus/metabolism; Esophagus/pathology; Hemoglobins/analysis; Hemoglobins/chemistry; Hemoglobins/metabolism; Male; NF-kappa B/metabolism; Oxidative Stress/drug effects; Pilot Projects; Protein Serine-Threonine Kinases/metabolism; Rats; Rats, Sprague-Dawley; NF-kappaB-Inducing Kinase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tobacco Smoke Pollution / Bile Reflux / Epithelial Cells / Esophagitis / Esophagus Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Inhal Toxicol Journal subject: TOXICOLOGIA Year: 2011 Type: Article Affiliation country: United States

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