A subset of interleukin-21+ chemokine receptor CCR9+ T helper cells target accessory organs of the digestive system in autoimmunity.

McGuire, Helen M; Vogelzang, Alexis; Ma, Cindy S; Hughes, William E; Silveira, Pablo A; Tangye, Stuart G; Christ, Daniel; Fulcher, David; Falcone, Marika; King, Cecile

McGuire, Helen M; Vogelzang, Alexis; Ma, Cindy S; Hughes, William E; Silveira, Pablo A; Tangye, Stuart G; Christ, Daniel; Fulcher, David; Falcone, Marika; King, Cecile.

Affiliation

McGuire HM; Department of Immunology, The Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010, Australia.

Immunity ; 34(4): 602-15, 2011 Apr 22.

Article in En | MEDLINE | ID: mdl-21511186

Subject(s)

Autoimmunity; Interleukins/immunology; Islets of Langerhans/immunology; Receptors, CCR/immunology; T-Lymphocytes, Helper-Inducer/immunology; Animals; B-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/cytology; CD8-Positive T-Lymphocytes/immunology; Cell Movement; Cell Survival; Diabetes Mellitus/immunology; Female; Humans; Interleukins/biosynthesis; Mice; Mice, Knockout; Receptors, Interleukin-21/deficiency; Receptors, Interleukin-21/immunology; Sjogren's Syndrome/immunology; T-Lymphocytes, Helper-Inducer/cytology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoimmunity / Islets of Langerhans / Interleukins / T-Lymphocytes, Helper-Inducer / Receptors, CCR Limits: Animals / Female / Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2011 Type: Article Affiliation country: Australia

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