IGF1-R signals through the RON receptor to mediate pancreatic cancer cell migration.

Jaquish, Dawn V; Yu, Peter T; Shields, David J; French, Randall P; Maruyama, Karly P; Niessen, Sherry; Hoover, Heather; A Cheresh, David; Cravatt, Ben; Lowy, Andrew M

Jaquish, Dawn V; Yu, Peter T; Shields, David J; French, Randall P; Maruyama, Karly P; Niessen, Sherry; Hoover, Heather; A Cheresh, David; Cravatt, Ben; Lowy, Andrew M.

Affiliation

Jaquish DV; Department of Surgery, Division of Surgical Oncology, Moores Cancer Center, University of California, 3855 Health Sciences Drive, San Diego, CA 92093-0987, USA.

Carcinogenesis ; 32(8): 1151-6, 2011 Aug.

Article in En | MEDLINE | ID: mdl-21565828

Subject(s)

Cell Movement/physiology; Pancreatic Neoplasms/metabolism; Pancreatic Neoplasms/pathology; Receptor Protein-Tyrosine Kinases/metabolism; Receptor, IGF Type 1/metabolism; Signal Transduction; Blotting, Western; Cell Adhesion; Humans; Immunoprecipitation; Pancreatic Neoplasms/genetics; RNA, Small Interfering/genetics; Receptor Protein-Tyrosine Kinases/antagonists & inhibitors; Receptor Protein-Tyrosine Kinases/genetics; Tumor Cells, Cultured; Wound Healing

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Signal Transduction / Cell Movement / Receptor, IGF Type 1 / Receptor Protein-Tyrosine Kinases Type of study: Prognostic_studies Limits: Humans Language: En Journal: Carcinogenesis Year: 2011 Type: Article Affiliation country: United States

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