Distribution of chloroquine in ocular tissue of pigmented rat using matrix-assisted laser desorption/ionization imaging quadrupole time-of-flight tandem mass spectrometry.

Yamada, Yasuhiro; Hidefumi, Kaji; Shion, Henry; Oshikata, Motoji; Haramaki, Yukari

Yamada, Yasuhiro; Hidefumi, Kaji; Shion, Henry; Oshikata, Motoji; Haramaki, Yukari.

Affiliation

Yamada Y; DMPK Department I, DMPK Research Laboratory, Research Division, Mitsubishi Tanabe Pharma Corporation, Saitama, Japan.

Rapid Commun Mass Spectrom ; 25(11): 1600-8, 2011 Jun 15.

Article in En | MEDLINE | ID: mdl-21594935

Subject(s)

Chloroquine/analysis; Chloroquine/pharmacokinetics; Eye/chemistry; Eye/metabolism; Melanins/metabolism; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods; Tandem Mass Spectrometry/methods; Administration, Oral; Animals; Chloroquine/administration & dosage; Histocytochemistry; Male; Melanins/chemistry; Molecular Imaging/methods; Rats; Tissue Distribution

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chloroquine / Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Eye / Tandem Mass Spectrometry / Melanins Limits: Animals Language: En Journal: Rapid Commun Mass Spectrom Year: 2011 Type: Article Affiliation country: Japan

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