RAC2, AEP, and ICAM1 expression are associated with CNS disease in a mouse model of pre-B childhood acute lymphoblastic leukemia.

Holland, Mark; Castro, Fernanda V; Alexander, Seema; Smith, Duncan; Liu, Jizhong; Walker, Michael; Bitton, Danny; Mulryan, Kate; Ashton, Garry; Blaylock, Morgan; Bagley, Steve; Connolly, Yvonne; Bridgeman, John; Miller, Crispin; Krishnan, Shekhar; Dempsey, Clare; Masurekar, Ashish; Stern, Peter; Whetton, Anthony; Saha, Vaskar

Holland, Mark; Castro, Fernanda V; Alexander, Seema; Smith, Duncan; Liu, Jizhong; Walker, Michael; Bitton, Danny; Mulryan, Kate; Ashton, Garry; Blaylock, Morgan; Bagley, Steve; Connolly, Yvonne; Bridgeman, John; Miller, Crispin; Krishnan, Shekhar; Dempsey, Clare; Masurekar, Ashish; Stern, Peter; Whetton, Anthony; Saha, Vaskar.

Affiliation

Holland M; Cancer Research UK Children's Cancer Group, Manchester Academic Health Science Centre, School of Cancer & Enabling Sciences, University of Manchester, Manchester, United Kingdom.

Blood ; 118(3): 638-49, 2011 Jul 21.

Article in En | MEDLINE | ID: mdl-21606482

Subject(s)

Central Nervous System Neoplasms/physiopathology; Cysteine Endopeptidases/genetics; Intercellular Adhesion Molecule-1/genetics; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/physiopathology; rac GTP-Binding Proteins/genetics; Animals; Cell Adhesion/physiology; Cell Line, Tumor; Cell Membrane/physiology; Central Nervous System Neoplasms/genetics; Central Nervous System Neoplasms/pathology; Child; Cysteine Endopeptidases/metabolism; Disease Models, Animal; Gene Expression Regulation, Leukemic/physiology; Humans; Intercellular Adhesion Molecule-1/metabolism; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/genetics; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/pathology; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology; Precursor Cell Lymphoblastic Leukemia-Lymphoma/physiopathology; Proteomics; rac GTP-Binding Proteins/metabolism; RAC2 GTP-Binding Protein

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cysteine Endopeptidases / Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Central Nervous System Neoplasms / Intercellular Adhesion Molecule-1 / Rac GTP-Binding Proteins Type of study: Risk_factors_studies Limits: Animals / Child / Humans Language: En Journal: Blood Year: 2011 Type: Article Affiliation country: United kingdom

Fulltext

XML

PubMed Links

Search on Google