Multiple oligomerization domains of KANK1-PDGFRß are required for JAK2-independent hematopoietic cell proliferation and signaling via STAT5 and ERK.

Medves, Sandrine; Noël, Laura A; Montano-Almendras, Carmen P; Albu, Roxana I; Schoemans, Hélène; Constantinescu, Stefan N; Demoulin, Jean-Baptiste

Medves, Sandrine; Noël, Laura A; Montano-Almendras, Carmen P; Albu, Roxana I; Schoemans, Hélène; Constantinescu, Stefan N; Demoulin, Jean-Baptiste.

Affiliation

Medves S; de Duve Institute, Université Catholique de Louvain, Brussels, Belgium.

Haematologica ; 96(10): 1406-14, 2011 Oct.

Article in En | MEDLINE | ID: mdl-21685469

Subject(s)

Extracellular Signal-Regulated MAP Kinases/metabolism; Janus Kinase 2/metabolism; Oncogene Proteins, Fusion/metabolism; Receptor, Platelet-Derived Growth Factor beta/metabolism; STAT5 Transcription Factor/metabolism; Signal Transduction; Tumor Suppressor Proteins/metabolism; Adaptor Proteins, Signal Transducing; Cell Line, Transformed; Cell Proliferation; Cytoskeletal Proteins; Gene Expression Regulation, Neoplastic; HEK293 Cells; Hematopoietic Stem Cells/metabolism; Humans; Myeloproliferative Disorders/genetics; Myeloproliferative Disorders/metabolism; Oncogene Proteins, Fusion/genetics; Phosphorylation; Protein Multimerization; Protein Structure, Tertiary; Receptor, Platelet-Derived Growth Factor beta/genetics; Tumor Suppressor Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Oncogene Proteins, Fusion / Receptor, Platelet-Derived Growth Factor beta / Tumor Suppressor Proteins / Extracellular Signal-Regulated MAP Kinases / STAT5 Transcription Factor / Janus Kinase 2 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Haematologica Year: 2011 Type: Article Affiliation country: Belgium

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