Chimeric Chikungunya viruses are nonpathogenic in highly sensitive mouse models but efficiently induce a protective immune response.

Wang, Eryu; Kim, Dal Young; Weaver, Scott C; Frolov, Ilya

Wang, Eryu; Kim, Dal Young; Weaver, Scott C; Frolov, Ilya.

Affiliation

Wang E; Institute for Human Infections and Immunity, Sealy Center for Vaccine Development, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.

J Virol ; 85(17): 9249-52, 2011 Sep.

Article in En | MEDLINE | ID: mdl-21697494

Subject(s)

Alphavirus Infections/immunology; Alphavirus Infections/prevention & control; Chikungunya virus/immunology; Chikungunya virus/pathogenicity; Viral Vaccines/genetics; Viral Vaccines/immunology; Animals; Antibodies, Neutralizing/blood; Antibodies, Viral/blood; Disease Models, Animal; Mice; Rodent Diseases/immunology; Rodent Diseases/virology; Vaccines, Attenuated/genetics; Vaccines, Attenuated/immunology; Vaccines, Synthetic/genetics; Vaccines, Synthetic/immunology

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Vaccines / Chikungunya virus / Alphavirus Infections Type of study: Diagnostic_studies Limits: Animals Language: En Journal: J Virol Year: 2011 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google