Antineoplastic Agents/pharmacology; Intracellular Signaling Peptides and Proteins/metabolism; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/metabolism; Protein-Tyrosine Kinases/metabolism; Pyrimidines/pharmacology; src-Family Kinases/metabolism; Antigens, CD/genetics; Antigens, CD/metabolism; Antigens, Neoplasm; Base Sequence; Cell Adhesion Molecules/genetics; Cell Adhesion Molecules/metabolism; Drug Resistance, Neoplasm/genetics; Drug Resistance, Neoplasm/physiology; Female; Fusion Proteins, bcr-abl/metabolism; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins/antagonists & inhibitors; Intracellular Signaling Peptides and Proteins/genetics; K562 Cells; Male; Neoplasm Proteins/genetics; Neoplasm Proteins/metabolism; Phosphorylation; Protein-Tyrosine Kinases/antagonists & inhibitors; Protein-Tyrosine Kinases/genetics; Proteomics; Proto-Oncogene Proteins/metabolism; RNA, Small Interfering/genetics; Receptor Protein-Tyrosine Kinases/metabolism; Signal Transduction; Syk Kinase; src-Family Kinases/genetics; Axl Receptor Tyrosine Kinase