An observational cohort study of the kynurenine to tryptophan ratio in sepsis: association with impaired immune and microvascular function.

Darcy, Christabelle J; Davis, Joshua S; Woodberry, Tonia; McNeil, Yvette R; Stephens, Dianne P; Yeo, Tsin W; Anstey, Nicholas M

Darcy, Christabelle J; Davis, Joshua S; Woodberry, Tonia; McNeil, Yvette R; Stephens, Dianne P; Yeo, Tsin W; Anstey, Nicholas M.

Affiliation

Darcy CJ; Global Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Northern Territory, Australia.

PLoS One ; 6(6): e21185, 2011.

Article in En | MEDLINE | ID: mdl-21731667

Subject(s)

Immunity/immunology; Kynurenine/blood; Microvessels/physiopathology; Sepsis/blood; Sepsis/immunology; Tryptophan/blood; Cohort Studies; Cytokines/blood; Endothelium, Vascular/physiopathology; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase/metabolism; Lymphocyte Count; Male; Microvessels/pathology; Middle Aged; Models, Biological; Sepsis/enzymology; Sepsis/physiopathology; Severity of Illness Index

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tryptophan / Sepsis / Microvessels / Immunity / Kynurenine Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2011 Type: Article Affiliation country: Australia

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