The nucleophosmin-anaplastic lymphoma kinase oncogene interacts, activates, and uses the kinase PIKfyve to increase invasiveness.

Dupuis-Coronas, Sophie; Lagarrigue, Frédéric; Ramel, Damien; Chicanne, Gaëtan; Saland, Estelle; Gaits-Iacovoni, Frédérique; Payrastre, Bernard; Tronchère, Hélène

Dupuis-Coronas, Sophie; Lagarrigue, Frédéric; Ramel, Damien; Chicanne, Gaëtan; Saland, Estelle; Gaits-Iacovoni, Frédérique; Payrastre, Bernard; Tronchère, Hélène.

Affiliation

Dupuis-Coronas S; INSERM, U1048, I2MC, Université Toulouse III Paul-Sabatier, Centre Hospitalier Universitaire de Toulouse, Toulouse Cedex 4, France.

J Biol Chem ; 286(37): 32105-14, 2011 Sep 16.

Article in En | MEDLINE | ID: mdl-21737449

Subject(s)

Cell Proliferation; Oncogene Proteins, Fusion/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Protein-Tyrosine Kinases/metabolism; Animals; Cell Line, Tumor; Cell Movement; Gene Silencing; Humans; Matrix Metalloproteinase 9/genetics; Matrix Metalloproteinase 9/metabolism; Mice; NIH 3T3 Cells; Neoplasm Invasiveness; Oncogene Proteins, Fusion/genetics; Phosphatidylinositol 3-Kinases/genetics; Protein-Tyrosine Kinases/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein-Tyrosine Kinases / Oncogene Proteins, Fusion / Phosphatidylinositol 3-Kinases / Cell Proliferation Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2011 Type: Article Affiliation country: France

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