A tight coupling between ß2Y97 and ß2F200 of the GABA(A) receptor mediates GABA binding.

Tran, Phu N; Laha, Kurt T; Wagner, David A

Tran, Phu N; Laha, Kurt T; Wagner, David A.

Affiliation

Tran PN; Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53201-1881, USA. phu.tran@marquette.edu

J Neurochem ; 119(2): 283-93, 2011 Oct.

Article in En | MEDLINE | ID: mdl-21806616

Subject(s)

Receptors, GABA-A/metabolism; gamma-Aminobutyric Acid/metabolism; Algorithms; Arginine/metabolism; Cells, Cultured; Chloride Channels/drug effects; Chloride Channels/metabolism; DNA, Complementary/biosynthesis; DNA, Complementary/genetics; Electrophysiological Phenomena; GABA Antagonists/metabolism; GABA Antagonists/pharmacology; HEK293 Cells; Humans; Kinetics; Models, Molecular; Mutagenesis; Patch-Clamp Techniques; Receptors, GABA-A/chemistry; Receptors, GABA-A/genetics; Transfection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, GABA-A / Gamma-Aminobutyric Acid Limits: Humans Language: En Journal: J Neurochem Year: 2011 Type: Article Affiliation country: United States

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