Xenobiotic metabolomics: major impact on the metabolome.

Johnson, Caroline H; Patterson, Andrew D; Idle, Jeffrey R; Gonzalez, Frank J

Johnson, Caroline H; Patterson, Andrew D; Idle, Jeffrey R; Gonzalez, Frank J.

Affiliation

Johnson CH; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA. caroline.johnson@nih.gov

Annu Rev Pharmacol Toxicol ; 52: 37-56, 2012.

Article in En | MEDLINE | ID: mdl-21819238

Subject(s)

Metabolome/drug effects; Metabolomics/methods; Xenobiotics/pharmacokinetics; Xenobiotics/toxicity; Animals; Biological Availability; Cyclophosphamide/pharmacokinetics; Cyclophosphamide/toxicity; Environmental Pollutants/toxicity; Fenofibrate/pharmacokinetics; Fenofibrate/toxicity; Genetic Variation; Humans; Ifosfamide/pharmacokinetics; Ifosfamide/toxicity; Inactivation, Metabolic; Metabolome/genetics; Metagenome/drug effects; Metagenome/genetics; Proteomics/methods

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Xenobiotics / Metabolome / Metabolomics Limits: Animals / Humans Language: En Journal: Annu Rev Pharmacol Toxicol Year: 2012 Type: Article Affiliation country: United States

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