Structural basis for the allosteric interference of myosin function by reactive thiol region mutations G680A and G680V.

Preller, Matthias; Bauer, Stefanie; Adamek, Nancy; Fujita-Becker, Setsuko; Fedorov, Roman; Geeves, Michael A; Manstein, Dietmar J

Preller, Matthias; Bauer, Stefanie; Adamek, Nancy; Fujita-Becker, Setsuko; Fedorov, Roman; Geeves, Michael A; Manstein, Dietmar J.

Affiliation

Preller M; Institut für Biophysikalische Chemie, Medizinische Hochschule Hannover, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany.

J Biol Chem ; 286(40): 35051-60, 2011 Oct 07.

Article in En | MEDLINE | ID: mdl-21841195

Subject(s)

Dictyostelium/metabolism; Mutation; Myosins/chemistry; Sulfhydryl Compounds/chemistry; Adenosine Diphosphate/chemistry; Allosteric Site; Binding Sites; Cold Temperature; Crystallography, X-Ray/methods; Kinetics; Models, Molecular; Mutagenesis; Principal Component Analysis; Temperature; Thermodynamics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfhydryl Compounds / Myosins / Dictyostelium / Mutation Language: En Journal: J Biol Chem Year: 2011 Type: Article Affiliation country: Germany

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