Nucleic acid-binding polymers as anti-inflammatory agents.

Lee, Jaewoo; Sohn, Jang Wook; Zhang, Ying; Leong, Kam W; Pisetsky, David; Sullenger, Bruce A

Lee, Jaewoo; Sohn, Jang Wook; Zhang, Ying; Leong, Kam W; Pisetsky, David; Sullenger, Bruce A.

Affiliation

Lee J; Duke Translational Research Institute, Duke University Medical Center, Durham, NC 27710, USA. jaewoo.lee@duke.edu

Proc Natl Acad Sci U S A ; 108(34): 14055-60, 2011 Aug 23.

Article in En | MEDLINE | ID: mdl-21844380

Subject(s)

Anti-Inflammatory Agents/pharmacology; Nucleic Acids/metabolism; Polymers/pharmacology; Animals; Anti-Inflammatory Agents/therapeutic use; Cations; Cell Line; Endocytosis/drug effects; Extracellular Space/drug effects; Extracellular Space/metabolism; Humans; Immunity/drug effects; Inflammation/pathology; Intracellular Space/drug effects; Intracellular Space/immunology; Ligands; Liver Diseases/complications; Liver Diseases/drug therapy; Mice; Mice, Inbred C57BL; Nucleic Acids/toxicity; Oligodeoxyribonucleotides/pharmacology; Polymers/therapeutic use; Shock, Septic/complications; Shock, Septic/drug therapy; Toll-Like Receptors/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymers / Nucleic Acids / Anti-Inflammatory Agents Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2011 Type: Article Affiliation country: United States

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