Cell polarity-determining proteins Par-3 and PP-1 are involved in epithelial tight junction defects in coeliac disease.

Schumann, Michael; Günzel, Dorothee; Buergel, Nataly; Richter, Jan F; Troeger, Hanno; May, Claudia; Fromm, Anja; Sorgenfrei, Detlef; Daum, Severin; Bojarski, Christian; Heyman, Martine; Zeitz, Martin; Fromm, Michael; Schulzke, Joerg-Dieter

Schumann, Michael; Günzel, Dorothee; Buergel, Nataly; Richter, Jan F; Troeger, Hanno; May, Claudia; Fromm, Anja; Sorgenfrei, Detlef; Daum, Severin; Bojarski, Christian; Heyman, Martine; Zeitz, Martin; Fromm, Michael; Schulzke, Joerg-Dieter.

Affiliation

Schumann M; Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Charité Berlin, Berlin, Germany.

Gut ; 61(2): 220-8, 2012 Feb.

Article in En | MEDLINE | ID: mdl-21865402

Subject(s)

Celiac Disease/metabolism; Cell Cycle Proteins/metabolism; Cell Polarity; Intestinal Mucosa/metabolism; Membrane Proteins/metabolism; Protein Phosphatase 1/metabolism; Tight Junctions/metabolism; Adaptor Proteins, Signal Transducing; Apoptosis; Biotinylation; Blotting, Western; Case-Control Studies; Celiac Disease/pathology; Celiac Disease/physiopathology; Cell Cycle Proteins/physiology; Claudins/metabolism; Humans; Intestinal Mucosa/chemistry; Membrane Proteins/physiology; Microscopy, Confocal; Phosphoproteins/metabolism; Polymerase Chain Reaction; Protein Phosphatase 1/physiology; Tight Junctions/chemistry; Zonula Occludens-1 Protein

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Celiac Disease / Cell Polarity / Cell Cycle Proteins / Tight Junctions / Protein Phosphatase 1 / Intestinal Mucosa / Membrane Proteins Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: En Journal: Gut Year: 2012 Type: Article Affiliation country: Germany

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