Hydrolytic mechanism of OXA-58 enzyme, a carbapenem-hydrolyzing class D ß-lactamase from Acinetobacter baumannii.

Verma, Vidhu; Testero, Sebastian A; Amini, Kaveh; Wei, William; Liu, Jerome; Balachandran, Naresh; Monoharan, Tharseekan; Stynes, Siobhan; Kotra, Lakshmi P; Golemi-Kotra, Dasantila

Verma, Vidhu; Testero, Sebastian A; Amini, Kaveh; Wei, William; Liu, Jerome; Balachandran, Naresh; Monoharan, Tharseekan; Stynes, Siobhan; Kotra, Lakshmi P; Golemi-Kotra, Dasantila.

Affiliation

Verma V; Department of Chemistry, York University, Toronto, Ontario M3J 1P3, Canada.

J Biol Chem ; 286(43): 37292-303, 2011 Oct 28.

Article in En | MEDLINE | ID: mdl-21880707

Subject(s)

Acinetobacter baumannii/enzymology; Anti-Bacterial Agents/chemistry; Bacterial Proteins/chemistry; Drug Resistance, Bacterial/physiology; Imipenem/chemistry; beta-Lactamases/chemistry; Anti-Bacterial Agents/pharmacology; Bacterial Proteins/metabolism; Catalysis; Hydrolysis; Imipenem/pharmacology; Protein Structure, Tertiary; Structural Homology, Protein; beta-Lactamases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Beta-Lactamases / Imipenem / Drug Resistance, Bacterial / Acinetobacter baumannii / Anti-Bacterial Agents Language: En Journal: J Biol Chem Year: 2011 Type: Article Affiliation country: Canada

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